Genetic Testing

ScanLinc is able to offer the first non-invasive pre-natal screening test that screens for single gene disorders.

Genesafe is the first non-invasive prenatal test that screens for both de novo and inherited single-gene disorders. Current non-invasive pre-natal tests (NIPT) screen for aneuploidies, microdeletions and some of the more advanced tests up to karyotype-level insight.

There are 3 different levels of testing:-

  • GeneSAFE™ Inherited which screens for 5 common inherited recessive genetic disorders, such as Cystic Fibrosis, β-Thalassemia, Sickle cell anemia, Deafness autosomal recessive type 1A, Deafness autosomal recessive type 1B
  • GeneSAFE™ DE NOVO screens for 44 severe genetic disorders due to de novo mutations (a gene mutation that has not been inherited) in 25 genes that cause skeletal dysplasia, congenital heart defects-, multiple congenital malformation syndromes, neurodevelopmental disorders, such as autism, epilepsy8, intellectual disability, and sporadic cases of various rare dominant Mendelian disorders, such as Schinzel-Giedion syndrome, and Bohring-Opitz syndrome
  • GeneSAFE™ Complete screens for both inherited and de novo single-gene disorders and represents a combination of the tests GeneSafe™ inherited and GeneSAFE™ de novo providing a complete picture of the pregnancy risk.

GeneSAFE™ works as a complementary screen to traditional or genome-wide NIPT (such as PrenatalSAFE® Karyo), allowing a complete picture of the risk of a pregnancy being affected by a genetic disorder. However Genesafe goes ONE STEP FURTHER… Through DNA analysis from maternal plasma, it screens for several clinically significant and life-altering genetic disorders that are not screened for with current NIPT technology.

+++a pre-conception test is also available to parents to be who may wish to be screened to identify if they are at risk of passing on inherited disorders to their unborn children – please enquire by email